Your goal is to get the Buffer length to around 10 ms sampleswith few or no new underruns added to the count. Underrun minimization will require some trial-and-error. If you do hear that sort of thing in an exported audio file, then it is likely a plugin behaving badly, check the plugin settings in that case. It is worth noting that underruns can ONLY occur in real-time playbackthey will not happen while exporting to wave or mp3 file. If the Audio Buffer runs dry, because your CPU or hard-drive can't keep up with the real-time audio stream, then your Soundcard will make rude pop, click or stutter noises. The Audio Buffer stores the audio data before it's sent to your audio interface. The good news is, CPU and disk usage can usually be lowered considerably if you take the time to make some adjustments to the FL Studio Audio settings.
If your CPU or disk usage climbs too high you will hear clicks or pops in the audio buffer underruns.